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The future of breast reconstruction with the use of stem cells

University of Pittsburgh researchers are studying the potential use of stem cells, that come from the fat in our own bodies, for breast cancer reconstruction. Breast cancer survivors may one day be able to avoid the prospect of invasive breast surgeries. This approach uses the stem cells to regenerate tissue to develop into different specialized cell types.

When the fat-derived stem cells are injected under the skin in a rat model, the cellular combination eventually formed what the researchers describe as a mound of tissue. Dr. J. Peter Rubin, M.D., assistant professor of plastic and reconstructive surgery at the University of Pittsburgh School of Medicine, said "The surgical options for breast reconstruction involve either the use of implants or a procedure whereby fat tissue is taken from another part of the body is shaped into the form of a breast. Neither is ideal nor without risk. The use of adipose or fat derived stem cells may represent a better solution for soft tissue reconstruction in breast cancer patients".

Dr. Rubin has been given a three year grant from the National Cancer Institute to further explore this unique approach.

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